Trade between the support and resistance of a wedge requires multi time frames assessment, from observation, it works best with 5M, 15M and 1H.

To begin with, we need to identify a wedge is forming, such as this:

Then, check higher timeframe MACD is declining and expanding. Here's the 1H, just to ensure it aligned to the major trend that the wedge is going downward and that retest of resistance is futile. Both RSI and MACD are declining.

Then, we basically can short this but check 1M or 5M for entry. You can see divergence:

As you can see from multi time frame here. 1H MACD and RSI is heading down and 15M MACD and RSI has cross over middle neutral level. It's an indicator a retest of resistance will most likely wont succeed. In the other hand 1M and 5M will be turning bullish. An indication of short term bullish.

Then, we finally reaching to an accumulation phase. Price action went sideway for a bit. From here, you can see 1M and 5M are screaming bullish but in 15M and 1H, that's a different story. There are rooms to retrace for 15M and 1H is definitely has turned bearish. Here, we need to wait for divergence to form. Price dipped lower but MACD and RSI for 15M and 5M said otherwise.

Then we see a pump, we need to focus on that breakout. Lets check higher timeframe again. 1H remain bearish (RSI and MACD), that's the overall trend, 15M is neutral now, hover at the neutral level for MACD and RSI.

In lower time frame 1M and 5M, divergence for RSI and MACD have formed, which means, this breakout was a fake breakout.

For this one, price broke down violently because of BTC also broke down. It fell out of the wedge but immediately found its support. And it starts its accumulation phase.

You can see it has this double bottom. Then check the 1H again - still bearish for both RSI and MACD. 15M can see MACD and RSI inclining forming a divergence.

It did break out and hit the upper resistance of the wedge and failed to broke 5M 100SMA. The buyers are getting weaker now.

1H - Bearish. MACD and RSI still declining. 15M - Bearish - Neutral. 1M has divergence formed. 5M - price failed to break through 100SMA.

But what be aware is the price probably will make a High Low because 1H MACD is getting tight now. And previously accumulation has also form a strong support. Check out 1M or 5M for reversal and also entry. When the price made a Higher Low, it means sellers are getting weak. A falling wedge can't be falling forever, usually around 3 waves. This one has 3 waves and failed to break up, this one is second break out.